So, antibiotic resistance – what do we know about it? Well, over the last ten years or so, harmful bacteria appear to be even more harmful. It seems as though we are losing our battle to control mother nature and her bacteria.
Where in the past antibiotics have controlled and contained bacteria and disease. However, it appears as though some bacteria is beginning to resist the effects of antibiotics.
What could the solution to this be? Perhaps you may feel that developing new classes of antibiotics may be the best course of action to take? Well, maybe you need to think again! Attempts to do exactly this, have been slowed to the point of halting.
If you want confirmation that this is the case, peruse the British Journal of Pharmacology, published in 2011, read its content and see what you can pull from its pages.
One thing that should jump out to you, although maybe not for all of the right reasons, is that in the 22 years between 1940 and 1962, there was nothing short of 20 classes of antibiotics available.
This does, and should, sound like an awful lot to be on the market given that those dates now seem so far away it is almost impossible for some of the modern generations to consider what life would even have been like at the time.
However, since 1962, only two new classes have found their way onto the market.
This may sound bad, however, it has not been too much of an issue over the years, as developing those that were on the market already, were managing to deal with those bacteria attacking the human body, relatively comfortably.
Which is of course, where antibiotic resistance comes into play, as something of a gamechanger – or in this case, a potential life changer.
So, what can possibly alter this apparent negativity? As you can likely infer from the title of the article, the answer could lie with cannabinoid antibiotics, which are developed from hemp and cannabis.
Are We Under Threat?
In short, perhaps. It is also possible that humanity needs to take a large portion of the blame for the increased threat of antibiotic resistance. Have you ever taken an antibiotic when it wasn’t medically necessary?
If yes, it is not a surprise, they are misused far more frequently than you would imagine – in fact, they are misused up to 50 percent of the time, so says the Centers for Disease Control and Prevention.
For your own health, you should stop misusing these antibiotics. There are certainly no benefits to doing so. All that it does is give bacteria the best chance of adapting to the antibiotics and becoming resistant, through constant exposure to them.
As you can imagine, this will carry significant risks to both yourself and the wider community.
A few choice statistics may well help you reach this decision at a significantly increased speed. For example, it is estimated that yearly there are more than 70,000 MRSA infections, with more than 9,000 leading to deaths, just in the United States of America.
Or else, the fact that the ex-director of the World Health Organization, Dr. Margaret Chan, referred to the resistance of bacteria to antibiotics as a ‘major global threat’ three years ago, back in 2016.
Things do not appear to be improving, on the whole, and when Dr. Chan made her statement back in 2016, the World Health Organisation also made the estimate that the frequency that antibiotic resistance would lead to fatalities could increase further and reach an astounding 10 million in just a few decades, when the calendar reaches 2050.
For the potential answer to any of these questions, we must journey back a good-while to the 1950s. It was in this decade that the medicinal, and more specifically the antibiotic potential of the cannabis plant, and by extension cannabinoids, began to be studied for the first time.
That is to say, for the first time in modern-day society. The actual origins of the medical use of the plant are way back in past times, from ancient civilizations such as the famous Egyptian civilization.
Anyway, back to modern history. In the ’50s, cannabis showed some signs that it could be used to develop a useful antiseptic – although the specifics of this were far from nailed down in the time, to say the least, it was still all up in the air.
Taking a swift journey forward, to 2008 to be specific. The findings of Giovanni Appendino and Simon Gibbons were published by the University of Eastern Piedmont and the University of London respectively.
These papers helped our knowledge of cannabinoids reach new levels. We may not know everything, in fact, that is something of an understatement. There are quite large amounts of information that is still not widely known to modern medical experts.
The most significant gap in our knowledge is, without doubt, the fact that still to this day, we are unsure why cannabinoid antibiotics are effective. On top of this, it is still not known how these effects would work in the human body. However, despite these somewhat vital gaps in our knowledge, a sense of optimism still remains around cannabinoids.
The Potential of CBD Antibiotics:
CBD is believed to be extremely potent against some strains of MRSA. Including two of those that are some of the most common strains of MRSA to be found in hospitals across the United Kingdom.
CBD has already been used to treat these strains of the illness and this result only adds to the estimation that cannabinoids could well be the future of modern medicine, working somewhat differently from other types of antibiotics that are widely available.
Other Strains of Antibiotics:
In their previously mentioned paper, Messer’s Appendino and Gibbons also noted that, aside from CBD, CBG also has the potential to be an exceptional antibiotic.
Cannabinol (hereafter CBN) and cannabichromene (CBC) also appear to share some of the qualities that could lead to them being considered as potential antibiotics in the future.
It goes without saying, that any antibiotic that is created from any strain of cannabis would have to be non-psychoactive. That is to say, it should not alter the mental state, thinking or wellbeing of any consumer. In short, this medicine should not give the user a ‘high’, in the same way, that consuming marijuana, for example, does.
It is not beyond the realms of possibility that a cannabinoid-based antibiotic could be developed. With all of CBD, CBG, CBN, and CBC all potentially having the correct effects to be developed into antibiotics.
THC is known for having psychoactive effects, which obviously seems somewhat contradictory to my previous statement just a few lines ago. However, it must be stressed that for all these effects are present, one will not be subject to the ‘high’ from applying THC to the skin.
As you can no doubt imagine, the potential of THC is naturally of interest to the scientific community.
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Cbd Oil Adviser have already touched on both the 1950s and 1960s in this article, so it seems somewhat prudent to highlight the fact that scientists began looking into THC and its range of medical benefits in the ’70s.
Initially, it was thoughts that, for all its benefits, THC would not be effective against gram-negative bacteria. However, research has come a long way since the 1970s and it is now thought that this may not be the case, following tests which saw its antibiotic efficiencies work against two types of gram-negative bacteria, one of which being E.coli.
Taking the Research Forward:
Modern research or current research should I say, has gone no-end to proving the uses of cannabis in the medical industry – that is to say when it is used properly. One need only look at CBD oil and the popularity of the product, to see the uses and wide appeal of such treatments.
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Such research is naturally an ongoing process, so just as is the case with regular medicines, please do not self-medicate, using any of the previously mentioned strains of antibiotics – especially those only in the experimental stages.
The hope is though, that such is the growing strength of this research, one day you may not need to. One day, doctors may prescribe these medicines for you.